At completion of this module, learners will be able to:
List groups of people who should receive high priority for latent TB infection (LTBI) treatment
Describe treatment regimens for LTBI
Describe treatment regimens for TB disease
Describe principles of preventing drug resistance
Describe patient monitoring during LTBI and TB disease treatment
Describe TB treatment adherence strategies
List common adverse reactions to drugs used to treat LTBI and TB disease

Treatment of LTBI
LTBI Treatment Regimens
Special Considerations for LTBI Treatment
Patient Medical Evaluation
Treatment of TB Disease
TB Disease Treatment Regimens and Dosage Recommendations
Special Considerations and Alternative Treatment Regimens
Treatment Monitoring Plan and Adverse Reactions
Adherence and Evaluating Patients’ Response to Treatment

Treatment of Latent TB Infection (LTBI)
LTBI is treated to prevent the development of TB disease
LTBI is treated with medication

Targeted testing should be used to identify and treat persons:
At high risk for infection with M. tuberculosis
At high risk for developing TB disease once infected with M. tuberculosis
People in these groups should receive high priority for LTBI treatment if they have a positive tuberculin skin test (TST) or interferon-gamma release assay (IGRA)

High Priority for LTBI Treatment
High-priority groups for LTBI treatment if positive IGRA or TST result of > 5 mm
Recent close contacts of people with infectious TB disease
People living with HIV
People with chest x-ray findings suggestive of previous TB disease
Patients with organ transplants
Other immunosuppressed patients..
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