Male and Female Infertility

Posted by e-Medical PPT Saturday, October 13, 2012
Definition
12 months of unprotected intercourse
Earlier for certain historical factors
Older than 35

Infertility Etiology
Female Factors:  35%
Unexplained: 28%
Male Factors:  24%
Other:  13%

Some sources list female factor as high as 50%

Female Factors Breakdown:
Ovarian Dysfunction:  21%
Tubal Factors: 14%

Ovulation Disorders:
Aging
Diminished ovarian reserve
Endocrine Disorder
Polycystic Ovary Syndrome (PCOS)
Tobacco Use
Premature Ovarian Failure

Tubal Factors:
Obstruction
History of Pelvic Inflammatory Disease (PID)
Tubal Surgery
Previous ectopic and salpingectomy

Uterine/Cervical Factors:
Congenital uterine anomaly
Fibroids
Polyps
Poor cervical mucus quantity/quality
Smoking
Infection
Uterine synechiae

Male Factors
Primary Hypogonadism:  30-40%
Altered Sperm Transport:  10-20%
Secondary Hypogonadism:  1-2%

Primary Hypogonadism: 
Cryptorchidism,Radiation,Testicular Trauma,Varicocele,Orchitis,Systemic disorder

Altered Sperm Transport:
Absent vas deferens or obstruction,Epididymal absence or obstruction,Erectile dysfunction (ED),Retrograde ejaculation

Secondary Hypogonadism:
Androgen/Estrogen excess,Infiltrative disorder (Sarcoid, TB),Pituitary adenoma,Trauma
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