Postsplenectomy sepsis_clinical features, management and prevention

Posted by e-Medical PPT Thursday, July 26, 2012
Introduction
PSS(Postsplenectomy sepsis)
Fulminant sepsis syndrome
usually due to S.pneumoniae
Pateint with impaired spleen function or s/p splenectomy both have risk

Role of spleen
The largest lymphoid organ
Filter senescent, rigid RBCs
Ingesting circulating bacteria
Production of antibodies

Common causes of theraputic splenectomy
Hemolytic anemia
Thrombocytopenia
Malignancy
Hypersplenism
Splenic trauma

Common causes of impaired spleen function
Hemoglobinopathy
Hemolysis
Congenital asplenia
Collagen vascular diseases
Allogenic bone marrow transplantation

Common pathogens
Encapsulated pathogen
Streptococcus pneumoniae(50~60 %)
 No particular serotype is more common
Haemophilus influezae(20~30 %)
Neisseria spp.(10~20 %)
Other uncommon pathogens:
 Capnocytophaga canimorsus
  Common flora in oral cavity of dogs and cats
 Bordetella holmesii
Related Posts Plugin for WordPress, Blogger...

0 Responses to Postsplenectomy sepsis_clinical features, management and prevention

Post a Comment

We are on Google+

Share This

GET UPDATES!!!

Subscribe by E-mail & receive updates your inbox!
Enter your email address:

Follow Us on Facebook

Blog Archive