Lung transplantation

Posted by e-Medical PPT Wednesday, March 14, 2012
Lung transplantation is a surgical procedure in which a patient's diseased lungs are partially or totally replaced by lungs which come from a donor.James Hardy of the University of Mississippi performed the first human lung transplant in 1963.Following a single-lung transplantation, the patient survived for 18 days. 
Lung transplantation is the therapeutic measure of last resort for patients with end-stage lung disease who have exhausted all other available treatments without improvement.
chronic obstructive pulmonary disease (COPD), including emphysema;
idiopathic pulmonary fibrosis;
cystic fibrosis;
idiopathic (formerly known as "primary") pulmonary hypertension;
alpha 1-antitrypsin deficiency;
replacing previously transplanted lungs that have since failed;
other causes, including bronchiectasis and sarcoidosis.

Types of lung transplant
Lobe
A lobe transplant is a surgery in which part of a living donor's lung is removed and used to replace part of recipient's diseased lung. This procedure usually involves the donation of lobes from two different people, thus replacing a single lung in the recipient. Donors who have been properly screened should be able to maintain a normal quality of life despite the reduction in lung volume.

Single-lung
Many patients can be helped by the transplantation of a single healthy lung. The donated lung typically comes from a donor who has been pronounced brain-dead.

Double-lung
Certain patients may require both lungs to be replaced. This is especially the case for people with cystic fibrosis, due to the bacterial colonisation commonly found within such patients' lungs; if only one lung were transplanted, bacteria in the native lung could potentially infect the newly transplanted organ.

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