Overactive bladder(OAB)

Posted by e-Medical PPT Monday, November 15, 2010
Overactive bladder(OAB) is a urological condition defined by "urgency, with or without urge incontinence, usually with frequency and nocturia." Frequency is usually defined as urinating more than 8 times a day.The etiology of Overactive bladder is unclear, and indeed there may be multiple possible causes. It is often associated with detrusor overactivity, a pattern of bladder muscle contraction observed during urodynamics, and treatments for OAB, are usually synonymous with treatments for detrusor overactivity. OAB is distinct from stress urinary incontinence, but when they occur together is usually known as mixed incontinence.
Treatment for OAB includes lifestyle modification (fluid restriction, avoidance of caffeine), bladder retraining, antimuscarinic drugs (darifenacin, hyoscyamine, oxybutynin, tolterodine, solifenacin, trospium), and various devices (Urgent PC Neuromodulation System, InterStim). Intravesical botulinum toxin A is also used in some intractable cases.

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