Gallbladder cancer

Posted by e-Medical PPT Monday, November 1, 2010
Gallbladder cancer is a relatively uncommon cancer.It is a rare cancer that is still being studied and thought to be related to gallstones building up, which also can lead to calcification of the gallbladder, a condition known as Porcelain gallbladder. Porcelain gallbladder is also rare. Some studies indicate that people with porcelain gallbladder have a high risk of developing gallbladder cancer.
Other risk factors
    * Gender: Approx. twice more common in women than men,
    * Obesity increases the risk for gallbladder cancer.
    * Primary carcinoma is linked to chronic cholecystitis and cholelithiasis.
Most tumors are adenocarcinomas, with a small percent being squamous cell carcinomas. The cancer commonly spreads to the liver, bile duct, stomach,and duodenum.
Early diagnosis is not generally possible.Transabdominal ultrasound, CT scan, endoscopic ultrasound, MRI, and Magnetic resonance cholangio-pancreatography (MRCP) can be used to diagnose.The most common and most effective treatment is cholecystectomy with part of liver and lymph node dissection.If surgery is not possible, endoscopic stenting of the biliary tree can reduce jaundice and a stent in stomach may relieve vomiting. Chemotherapy and radiation may also be used with surgery.

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