Renal Cystic Disease

Posted by e-Medical PPT Sunday, October 17, 2010
One third of people older than 50 years develop renal cysts. Although most are simple cysts, renal cystic disease has multiple etiologies. Broad categories of cystic disease include the following:
* Developmental -Multicystic dysplastic kidney (MCDK)
* Genetic -Autosomal recessive polycystic kidney disease (ARPKD), autosomal dominant polycystic kidney disease (ADPKD), juvenile nephronophthisis (JNPHP), medullary cystic kidney disease (MCKD)
* Cysts associated with systemic disease -Von Hippel-Lindau syndrome (VHLS), tuberous sclerosis (TS)
* Acquired - Simple cysts, acquired cystic renal disease, medullary sponge kidney (MSK)
* Malignancy -Cystic renal cell carcinoma
The most common larger cysts include acquired cysts, simple cysts, and cysts associated with ADPKD. Smaller cysts characterize ARPKD, JNPHP, MCKD, and MSK. In adults, renal angiomyolipomas and RCC may also have cystic components.

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