Systemic Lupus Erythematosus

Posted by e-Medical PPT Tuesday, September 14, 2010
Systemic lupus erythematosus is a chronic systemic autoimmune disease (or autoimmune connective tissue disease) that can affect any part of the body. SLE commonly attacks the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system.The disease occurs nine times more often in women than in men, especially between the ages of 15 and 50.
Common initial and chronic complaints include fever, malaise, joint pains, myalgias, fatigue, and temporary loss of cognitive abilities. Because they are so often seen with other diseases, these signs and symptoms are not part of the diagnostic criteria for SLE.
Dermatological manifestations
As many as 30% of sufferers have some dermatological symptoms,with 30% to 50% suffering from the classic malar or butterfly rash associated with the disease.Alopecia, mouth, nasal, and vaginal ulcers and lesions on the skin are also possible manifestations.
Musculoskeletal manifestations
The most commonly sought medical attention is for joint pain, with the small joints of the hand and wrist usually affected, although all joints are at risk.Unlike rheumatoid arthritis, lupus arthritis is less disabling and usually does not cause severe destruction of the joints.
Hematological manifestations
Anaemia may develop in up to 50% of cases. Low platelet and white blood cell counts may be due to the disease or a side-effect of pharmacological treatment. People with SLE may have an association with antiphospholipid antibody syndrome.
Cardiac manifestations
A person with SLE may have inflammation of various parts of the heart, such as pericarditis, myocarditis, and endocarditis. The endocarditis of SLE is characteristically noninfective (Libman-Sacks endocarditis) and involves either the mitral valve or the tricuspid valve...
Related Posts Plugin for WordPress, Blogger...

0 Responses to Systemic Lupus Erythematosus

Post a Comment

Share This


Subscribe by E-mail & receive updates your inbox!
Enter your email address:

Follow Us on Facebook

Blog Archive