Hirsutism and Virilization

Posted by e-Medical PPT Saturday, September 18, 2010
Hirsutism is the excessive hairiness on FEMALE in those parts of the body where terminal hair does not normally occur or is minimal.It refers to a male pattern of body hair and it is therefore primarily of cosmetic and psychological concern.Hirsutism is a symptom rather than a disease and may be a sign of a more serious medical condition, especially if it develops well after puberty.
Hirsutism can be caused by either an increased level of androgens, or an oversensitivity of hair follicles to androgens.


Causes of HIRSUTISM
* Polycystic ovary syndrome
* Congenital adrenal hyperplasia, in turn mostly caused by 21-α hydroxylase deficiency
* Cushing's disease
* Tumors in the ovaries or adrenal gland
* Use of drugs like Tetrahydrogestrinone
Virilization refers to concurrent presentation of Hirsutism with a board range of signs suggestive of androgen excess(ACNE,FRONTOTEMPORAL BALDING,DEPPENING OF THE VOICE ,A DECREASE IN BREAT SIZE
CLITORAL HYPERTROPHY)Prenatal virilization of a genetically female fetus can occur when an excessive amount of androgen is produced by the fetal adrenal glands or is present in maternal blood.In the severest form of congenital adrenal hyperplasia, complete masculinization of a genetically female fetus results in an apparently normal baby boy with no palpable testes. More often, the virilization is partial and the genitalia are ambiguous.

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