Myocarditis

Posted by e-Medical PPT Sunday, August 15, 2010
Myocarditis is inflammation of heart muscle.Myocarditis is most often due to infection by common viruses, such as parvovirus B19, less commonly non-viral pathogens such as Borrelia burgdorferi (Lyme disease) or Trypanosoma cruzi.The consequences of myocarditis thus also vary widely. It can cause a mild disease without any symptoms that resolves itself, or it may cause chest pain, heart failure, or sudden death.The signs and symptoms associated with myocarditis are varied, and relate either to the actual inflammation of the myocardium, or the weakness of the heart muscle.
Myocardial inflammation can be suspected on the basis of ECG, elevated CRP or ESR and increased IgM (serology) against viruses known to affect the myocardium.Markers of myocardial damage (troponin or creatine kinase cardiac isoenzymes) are elevated.The ECG findings most commonly seen in myocarditis are diffuse T wave inversions and saddle-shaped ST-segment elevations.Definitive diagnosis requires a biopsy of the myocardium.

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