DIFFERENTIAL DIAGNOSIS OF LEUKOCORIA

Posted by e-Medical PPT Friday, August 20, 2010
Leukocoria is an abnormal white reflection from the retina of the eye.Leukocoria can be seen in Cataract,Retinoblastoma,Toxocariasis,Coats disease,Retinopathy of prematurity,persistence of the tunica vasculosa lentis(PHPV),Retinal detachment,Coloboma,Retinal dysplasia and Norrie´s disease.Nontraumatic unilateral cataracts first detected after 6 months of age also present special concerns.Usually, the precise age of onset is not known.Retinoblastoma is the most common intraocular tumor of childhood, accounting for 1% of childhood cancer deaths in the United States and 5% of blindness in children.Congenital retinal telangiectasis (Coats' disease) is an idiopathic retinal vascular disorder that usually affects young male patients unilaterally in their first or second decade of life.Persistent hyperplastic primary vitreous (PHPV) is a congenital anomaly in which the primary vitreous fails to regress in utero. Highly vascular mesenchymal tissue nurtures the developing lens during intrauterine life. In PHPV, the mesenchymal tissue forms a mass behind the lens.Retinopathy of prematurity is the condition that Vasoproliferative retinopathy affecting premature infants exposed to high oxygen.

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