Platelets Disorders

Posted by e-Medical PPT Thursday, June 3, 2010
The hemostatic system consists of platelets, coagulation factors, and the endothelial cells lining the blood vessels. The platelets arise from the fragmentation of the cytoplasm megakaryocytes in the bone marrow and circulate in blood as disc-shaped anucleate particles.Platelet disorders lead to defects in primary hemostasis and are characterized by prolonged bleeding time, and the characteristic physical examination findings are petechiae and purpura.
Immune thrombocytopenic purpura (ITP) is one of the most common autoimmune disorders. It occurs in 2 distinct clinical types, an acute self-limiting form observed almost exclusively in children , and a chronic form, observed mostly in adults and rarely in children.ITP occurs commonly in otherwise healthy individuals and only rarely as the initial manifestation of lupus and other autoimmune disorders. Human immunodeficiency virus (HIV) infection is often associated with immune thrombocytopenia in both adults and children.

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2 Responses to Platelets Disorders

  1. Anonymous Says:
  2. AWESOME.........THANKS

  3. Admin Says:
  4. Thanks for your feedback!!!


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