Infectious Mononucleosis(THE KISSING DISEASE)

Posted by e-Medical PPT Wednesday, June 16, 2010
EBV is transmitted via intimate contact with body secretions, primarily oropharyngeal secretions. EBV infects the B cells in the oropharyngeal epithelium. The organism may also be shed from the uterine cervix, implicating the role of genital transmission in some cases. On rare occasion, EBV is spread via blood transfusion.
Circulating B cells spread the infection throughout the entire reticular endothelial system (liver, spleen, and peripheral lymph nodes). EBV infection of B lymphocytes results in a humoral and cellular response to the virus.
Early signs include fever, lymphadenopathy, pharyngitis, rash, and/or periorbital edema. Relative bradycardia has been described in some patients with EBV mononucleosis, but it is not a constant finding.
Later physical findings include hepatomegaly, palatal petechiae, jaundice, uvular edema, splenomegaly, and, rarely (1-2%), findings associated with splenic rupture.

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5 Responses to Infectious Mononucleosis(THE KISSING DISEASE)

  1. Anonymous Says:
  2. cool

  3. Anonymous Says:
  4. good rapid refreshment thx

  5. Anonymous Says:
  6. OMG!!! disease from a kiss

  7. Peralta Says:
  8. I think is wrong to name this disease as "the kissing disease", ´cause the biggest incidence of the virus infection is in kids.

  9. Anonymous Says:
  10. there is maculopapular rash if amoxicillin is given to treat tonsillitis


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