Acute myeloid leukemia

Posted by e-Medical PPT Sunday, May 16, 2010
Acute myeloid leukemia, is a cancer of the myeloid  line of blood cells, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells.The symptoms of AML are caused by replacement of normal bone marrow with leukemic cells, which causes pancytopenia.  As an acute leukemia, AML progresses rapidly and is typically fatal within weeks or months if left untreated.
AML has several subtypes; treatment and prognosis varies among subtypes. Five-year survival varies from 15–70%, and relapse rate varies from 78–33%, depending on subtype. AML is treated initially with chemotherapy aimed at inducing a remission; patients may go on to receive additional chemotherapy or a hematopoietic stem cell transplant.


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